Early myeloid-derived suppressor cells (HLA-DR(−)/(low)CD33(+)CD16(−)) expanded by granulocyte colony-stimulating factor prevent acute graft-versus-host disease (GVHD) in humanized mouse and might contribute to lower GVHD in patients post allo-HSCT

INTRODUCTION: Myeloid-derived suppressor cells (MDSCs) are proposed to control graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the definition of human MDSCs has not yet reached consensus, and the mechanism of MDSCs to control GVHD remains...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Lv, Meng, Chang, Ying-Jun, Zhao, Xiang-Yu, Zhao, Xiao-Su, Zhang, Yuan-Yuan, Sun, Yu-Qian, Wang, Zhi-Dong, Suo, Pan, Zhou, Yang, Liu, Dan, Zhai, Shu-Zhen, Hong, Yan, Wang, Yu, Zhang, Xiao-Hui, Xu, Lan-Ping, Liu, Kai-Yan, Huang, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423891/
https://www.ncbi.nlm.nih.gov/pubmed/30885244
http://dx.doi.org/10.1186/s13045-019-0710-0

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