Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing

The essence of precision medicine is to achieve the goal of “individualized treatment” through genotyping of patients and targeted therapy. At present, the pathogenic genes of non-small cell lung cancer (NSCLC) have been studied most thoroughly and targeted therapy based on genotyping has been the m...

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Autores principales: Dong, Jingsi, Li, Bingjie, Lin, Dan, Zhou, Qinghua, Huang, Depei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424010/
https://www.ncbi.nlm.nih.gov/pubmed/30930778
http://dx.doi.org/10.3389/fphar.2019.00230
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author Dong, Jingsi
Li, Bingjie
Lin, Dan
Zhou, Qinghua
Huang, Depei
author_facet Dong, Jingsi
Li, Bingjie
Lin, Dan
Zhou, Qinghua
Huang, Depei
author_sort Dong, Jingsi
collection PubMed
description The essence of precision medicine is to achieve the goal of “individualized treatment” through genotyping of patients and targeted therapy. At present, the pathogenic genes of non-small cell lung cancer (NSCLC) have been studied most thoroughly and targeted therapy based on genotyping has been the most successful. This paper focuses on the precision treatment of NSCLC based on genotyping, comparing gene detection methods and summarize the latest progress of NSCLC immunotherapy.
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spelling pubmed-64240102019-03-29 Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing Dong, Jingsi Li, Bingjie Lin, Dan Zhou, Qinghua Huang, Depei Front Pharmacol Pharmacology The essence of precision medicine is to achieve the goal of “individualized treatment” through genotyping of patients and targeted therapy. At present, the pathogenic genes of non-small cell lung cancer (NSCLC) have been studied most thoroughly and targeted therapy based on genotyping has been the most successful. This paper focuses on the precision treatment of NSCLC based on genotyping, comparing gene detection methods and summarize the latest progress of NSCLC immunotherapy. Frontiers Media S.A. 2019-03-12 /pmc/articles/PMC6424010/ /pubmed/30930778 http://dx.doi.org/10.3389/fphar.2019.00230 Text en Copyright © 2019 Dong, Li, Lin, Zhou and Huang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Dong, Jingsi
Li, Bingjie
Lin, Dan
Zhou, Qinghua
Huang, Depei
Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title_full Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title_fullStr Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title_full_unstemmed Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title_short Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
title_sort advances in targeted therapy and immunotherapy for non-small cell lung cancer based on accurate molecular typing
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424010/
https://www.ncbi.nlm.nih.gov/pubmed/30930778
http://dx.doi.org/10.3389/fphar.2019.00230
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