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Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)

BACKGROUND: Abdominal adiposity is a risk factor for cardiovascular disease. OBJECTIVE: To determine the magnitude of the association between abdominal adiposity, according to five different indicators, and the carotid intima-media thickness (CIMT). METHODS: Data from 8,449 participants aged 35 to 7...

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Autores principales: Eickemberg, Michaela, Amorim, Leila Denise Alves Ferreira, de Almeida, Maria da Conceição Chagas, de Aquino, Estela Maria Leão, da Fonseca, Maria de Jesus Mendes, Santos, Itamar de Souza, Chor, Dora, Diniz, Maria de Fátima Sander, Barreto, Sandhi Maria, de Matos, Sheila Maria Alvim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424038/
https://www.ncbi.nlm.nih.gov/pubmed/30916202
http://dx.doi.org/10.5935/abc.20180273
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author Eickemberg, Michaela
Amorim, Leila Denise Alves Ferreira
de Almeida, Maria da Conceição Chagas
de Aquino, Estela Maria Leão
da Fonseca, Maria de Jesus Mendes
Santos, Itamar de Souza
Chor, Dora
Diniz, Maria de Fátima Sander
Barreto, Sandhi Maria
de Matos, Sheila Maria Alvim
author_facet Eickemberg, Michaela
Amorim, Leila Denise Alves Ferreira
de Almeida, Maria da Conceição Chagas
de Aquino, Estela Maria Leão
da Fonseca, Maria de Jesus Mendes
Santos, Itamar de Souza
Chor, Dora
Diniz, Maria de Fátima Sander
Barreto, Sandhi Maria
de Matos, Sheila Maria Alvim
author_sort Eickemberg, Michaela
collection PubMed
description BACKGROUND: Abdominal adiposity is a risk factor for cardiovascular disease. OBJECTIVE: To determine the magnitude of the association between abdominal adiposity, according to five different indicators, and the carotid intima-media thickness (CIMT). METHODS: Data from 8,449 participants aged 35 to 74 years from the ELSA-Brazil study were used. The effect of waist circumference (WC), waist-to-hip ratio (WHR), conicity index (C index), lipid accumulation product (LAP) and visceral adiposity index (VAI) on CIMT were evaluated. Data were stratified by gender and analyzed using multivariate linear and logistic regressions. A significance level of 5% was considered. RESULTS: Participants with CIMT > P75 showed a higher frequency of abdominal adiposity (men >72% and women >66%) compared to those with CIMT < P75. Abdominal adiposity was associated with the mean CIMT, mainly through WC in men (0.04; 95%CI: 0.033; 0.058). The abdominal adiposity identified by the WC, WHR, LAP, and VAI indicators in women showed an effect of 0.02 mm on the CIMT (WC: 0.025, 95%CI: 0.016, 0.035; WHR: 0.026, 95%CI: 0.016, 0.035; LAP: 0.024, 95%CI: 0.014; 0.034; VAI: 0.020, 95%CI: 0.010, 0.031). In the multiple logistic regression, the abdominal adiposity diagnosed by WC showed an important effect on the CIMT in both genders (men: OR = 1.47, 95%CI: 1.22-1.77, women: OR = 1.38; 95%CI: 1.17-1.64). CONCLUSION: Abdominal adiposity, identified through WC, WHR, LAP, and VAI, was associated with CIMT in both genders, mainly for the traditional anthropometric indicator, WC.
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spelling pubmed-64240382019-03-21 Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil) Eickemberg, Michaela Amorim, Leila Denise Alves Ferreira de Almeida, Maria da Conceição Chagas de Aquino, Estela Maria Leão da Fonseca, Maria de Jesus Mendes Santos, Itamar de Souza Chor, Dora Diniz, Maria de Fátima Sander Barreto, Sandhi Maria de Matos, Sheila Maria Alvim Arq Bras Cardiol Original Article BACKGROUND: Abdominal adiposity is a risk factor for cardiovascular disease. OBJECTIVE: To determine the magnitude of the association between abdominal adiposity, according to five different indicators, and the carotid intima-media thickness (CIMT). METHODS: Data from 8,449 participants aged 35 to 74 years from the ELSA-Brazil study were used. The effect of waist circumference (WC), waist-to-hip ratio (WHR), conicity index (C index), lipid accumulation product (LAP) and visceral adiposity index (VAI) on CIMT were evaluated. Data were stratified by gender and analyzed using multivariate linear and logistic regressions. A significance level of 5% was considered. RESULTS: Participants with CIMT > P75 showed a higher frequency of abdominal adiposity (men >72% and women >66%) compared to those with CIMT < P75. Abdominal adiposity was associated with the mean CIMT, mainly through WC in men (0.04; 95%CI: 0.033; 0.058). The abdominal adiposity identified by the WC, WHR, LAP, and VAI indicators in women showed an effect of 0.02 mm on the CIMT (WC: 0.025, 95%CI: 0.016, 0.035; WHR: 0.026, 95%CI: 0.016, 0.035; LAP: 0.024, 95%CI: 0.014; 0.034; VAI: 0.020, 95%CI: 0.010, 0.031). In the multiple logistic regression, the abdominal adiposity diagnosed by WC showed an important effect on the CIMT in both genders (men: OR = 1.47, 95%CI: 1.22-1.77, women: OR = 1.38; 95%CI: 1.17-1.64). CONCLUSION: Abdominal adiposity, identified through WC, WHR, LAP, and VAI, was associated with CIMT in both genders, mainly for the traditional anthropometric indicator, WC. Sociedade Brasileira de Cardiologia - SBC 2019-03 /pmc/articles/PMC6424038/ /pubmed/30916202 http://dx.doi.org/10.5935/abc.20180273 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Eickemberg, Michaela
Amorim, Leila Denise Alves Ferreira
de Almeida, Maria da Conceição Chagas
de Aquino, Estela Maria Leão
da Fonseca, Maria de Jesus Mendes
Santos, Itamar de Souza
Chor, Dora
Diniz, Maria de Fátima Sander
Barreto, Sandhi Maria
de Matos, Sheila Maria Alvim
Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title_full Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title_fullStr Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title_full_unstemmed Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title_short Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)
title_sort indicators of abdominal adiposity and carotid intima-media thickness: results from the longitudinal study of adult health (elsa-brazil)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424038/
https://www.ncbi.nlm.nih.gov/pubmed/30916202
http://dx.doi.org/10.5935/abc.20180273
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