Loss of the TAM Receptor Axl Ameliorates Severe Zika Virus Pathogenesis and Reduces Apoptosis in Microglia

The TAM receptor, Axl, has been implicated as a candidate entry receptor for Zika virus (ZIKV) infection but has been shown as inessential for virus infection in mice. To probe the role of Axl in murine ZIKV infection, we developed a mouse model lacking the Axl receptor and the interferon alpha/beta...

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Detalles Bibliográficos
Autores principales: Hastings, Andrew K., Hastings, Katherine, Uraki, Ryuta, Hwang, Jesse, Gaitsch, Hallie, Dhaliwal, Khushwant, Williamson, Eric, Fikrig, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424058/
https://www.ncbi.nlm.nih.gov/pubmed/30884311
http://dx.doi.org/10.1016/j.isci.2019.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424058/
https://www.ncbi.nlm.nih.gov/pubmed/30884311
http://dx.doi.org/10.1016/j.isci.2019.03.003

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