Cargando…

Cytomegalovirus-specific CD8+ T-cells are associated with a reduced incidence of early relapse after allogeneic stem cell transplantation

Leukemia relapse is the main cause for mortality after allogeneic stem cell transplantation (allo-SCT). Donor-derived allo-immune responses eliminate the residual host hematopoiesis and protect against relapse. Cytomegalovirus (CMV) reactivation (CMV-R) after allo-SCT may trigger anti-leukemic effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varanasi, Pavankumar Reddy, Ogonek, Justyna, Luther, Susanne, Dammann, Elke, Stadler, Michael, Ganser, Arnold, Borchers, Sylvia, Hambach, Lothar, Weissinger, Eva M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424430/ https://www.ncbi.nlm.nih.gov/pubmed/30889204 http://dx.doi.org/10.1371/journal.pone.0213739

Ejemplares similares

Human CD8+ CD57- T(EMRA) cells: Too young to be called "old"
por: Verma, Kriti, et al.
Publicado: (2017)

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation
por: Ogonek, Justyna, et al.
Publicado: (2016)

Adaptive NK cells undergo a dynamic modulation in response to human cytomegalovirus and recruit T cells in in vitro migration assays
por: Basílio-Queirós, Débora, et al.
Publicado: (2022)

Sequential Anti-Cytomegalovirus Response Monitoring May Allow Prediction of Cytomegalovirus Reactivation after Allogeneic Stem Cell Transplantation
por: Borchers, Sylvia, et al.
Publicado: (2012)

Correction: Sequential Anti-Cytomegalovirus Response Monitoring May Allow Prediction of Cytomegalovirus Reactivation after Allogeneic Stem Cell Transplantation
por: Borchers, Sylvia, et al.
Publicado: (2013)

miR-625-3p is upregulated in CD8+ T cells during early immune reconstitution after allogeneic stem cell transplantation
por: Verma, Kriti, et al.
Publicado: (2017)

The graft-versus-leukemia effect of prophylactic donor lymphocyte infusions after allogeneic stem cell transplantation is equally effective in relapse prevention but safer compared to spontaneous graft-versus-host disease
por: Stadler, Michael, et al.
Publicado: (2023)

Improving Safety of Preemptive Therapy with Oral Valganciclovir for Cytomegalovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation
por: Barkam, Corinna, et al.
Publicado: (2012)

Long term follow up of patients after allogeneic stem cell transplantation and transfusion of HSV-TK transduced T-cells
por: Weissinger, Eva M., et al.
Publicado: (2015)

Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor
por: Bunse, Carola E., et al.
Publicado: (2013)

Possible Role of Minor H Antigens in the Persistence of Donor Chimerism after Stem Cell Transplantation; Relevance for Sustained Leukemia Remission
por: van der Torren, Cornelis R., et al.
Publicado: (2015)

Navigating preemptive and therapeutic donor lymphocyte infusions in advanced myeloid malignancies by high-sensitivity chimerism analysis
por: Stadler, Michael, et al.
Publicado: (2022)

Donor Vδ1(+) γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL
por: Prinz, Immo, et al.
Publicado: (2013)

Severe allo-immune antibody-associated peripheral and central nervous system diseases after allogeneic hematopoietic stem cell transplantation
por: Hümmert, Martin W., et al.
Publicado: (2021)

B-Cell-Based and Soluble Biomarkers in Body Liquids for Predicting Acute/Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation
por: Juric, Mateja Kralj, et al.
Publicado: (2017)

Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand
por: Tomić, Adriana, et al.
Publicado: (2016)

VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation
por: Sethi, Maya K., et al.
Publicado: (2017)

Spectral flow cytometry cluster analysis of therapeutic donor lymphocyte infusions identifies T cell subsets associated with outcome in patients with AML relapse
por: Odak, Ivan, et al.
Publicado: (2022)

Is allogeneic transplantation the preferred therapy for older patients with acute myeloid leukemia?
por: Ganser, Arnold
Publicado: (2022)

Proteomic peptide profiling for preemptive diagnosis of acute graft-versus-host disease after allogeneic stem cell transplantation
por: Weissinger, E M, et al.
Publicado: (2013)

Milestones of Hematopoietic Stem Cell Transplantation – From First Human Studies to Current Developments
por: Juric, Mateja Kralj, et al.
Publicado: (2016)

A42 Next-generation sequencing to analyze multiple-strain infections, genotype distribution, and antiviral resistance in hematopoietic stem cell transplantation recipients with human cytomegalovirus infection
por: Dhingra, A, et al.
Publicado: (2019)

Cytomegalovirus (CMV) genotype in allogeneic hematopoietic stem cell transplantation
por: Dieamant, Débora C, et al.
Publicado: (2013)

Cytomegalovirus monitoring in allogeneic haemopoietic stem cell transplant recipients
por: Ramalingam, S., et al.
Publicado: (2006)

Treatment of Relapsed Acute Myeloid Leukemia
por: Thol, Felicitas, et al.
Publicado: (2020)

Impact of cytomegalovirus reactivation on relapse and survival in patients with acute leukemia who received allogeneic hematopoietic stem cell transplantation in first remission
por: Yoon, Jae-Ho, et al.
Publicado: (2016)

Another tool against cytomegalovirus after allogeneic hematopoietic cell transplantation
por: Chen, George L., et al.
Publicado: (2023)

Human cytomegalovirus multiple-strain infections and viral population diversity in haematopoietic stem cell transplant recipients analysed by high-throughput sequencing
por: Dhingra, A., et al.
Publicado: (2021)

T-cell receptor repertoire of cytomegalovirus-specific cytotoxic T-cells after allogeneic stem cell transplantation
por: Toya, Takashi, et al.
Publicado: (2020)

Letermovir for Prophylaxis and Pre-emptive Therapy of Cytomegalovirus Infection in Paediatric Allogeneic Haematopoietic Cell Transplant Patients
por: Körholz, Katharina F., et al.
Publicado: (2022)

Human Regulatory T Cells of G-CSF Mobilized Allogeneic Stem Cell Donors Qualify for Clinical Application
por: Ukena, Sya N., et al.
Publicado: (2012)

Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients
por: Stern, Lauren, et al.
Publicado: (2019)

Cellular Therapeutic Approaches to Cytomegalovirus Infection Following Allogeneic Stem Cell Transplantation
por: Shafat, Manar S., et al.
Publicado: (2020)

Intrathecal cytomegalovirus immunoglobulin for CMV encephalitis post allogeneic stem cell transplantation
por: Pang, Ian, et al.
Publicado: (2022)

Haploidentical versus unrelated allogeneic stem cell transplantation for relapsed/refractory acute myeloid leukemia: a report on 1578 patients from the Acute Leukemia Working Party of the EBMT
por: Brissot, Eolia, et al.
Publicado: (2019)

Clonal expansion of CD8(+) T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
por: Schultze-Florey, Christian R., et al.
Publicado: (2021)

Factors associated with cytomegalovirus infection in children undergoing allogeneic hematopoietic stem-cell transplantation
por: Jaing, Tang-Her, et al.
Publicado: (2019)

The association of conditioning regimen with cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation
por: Mardani, Masoud, et al.
Publicado: (2020)

MRD as Biomarker for Response to Donor Lymphocyte Infusion after Allogeneic Hematopoietic Cell Transplantation in Patients with AML
por: Teich, Katrin, et al.
Publicado: (2023)

Donor cell-derived myelofibrosis relapse after allogeneic stem cell transplantation
por: Chiusolo, Patrizia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0pjdamse35141sbd8g8u5udk4r