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Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity
Zika virus (ZIKV) is a mosquito-borne positive sense RNA virus. Recently, ZIKV emerged into the Western hemisphere as a human health threat, with severe disease associated with developmental and neurological complications. The structural envelope protein of ZIKV and other neurotropic flaviviruses co...
Autores principales: | Dinnon III, Kenneth H., Gallichotte, Emily N., Fritch, Ethan J., Menachery, Vineet D., Baric, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424462/ https://www.ncbi.nlm.nih.gov/pubmed/30845254 http://dx.doi.org/10.1371/journal.pntd.0007212 |
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