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Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity

Zika virus (ZIKV) is a mosquito-borne positive sense RNA virus. Recently, ZIKV emerged into the Western hemisphere as a human health threat, with severe disease associated with developmental and neurological complications. The structural envelope protein of ZIKV and other neurotropic flaviviruses co...

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Detalles Bibliográficos
Autores principales: Dinnon III, Kenneth H., Gallichotte, Emily N., Fritch, Ethan J., Menachery, Vineet D., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424462/
https://www.ncbi.nlm.nih.gov/pubmed/30845254
http://dx.doi.org/10.1371/journal.pntd.0007212

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