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A stochastic simulation of skeletal muscle calcium transients in a structurally realistic sarcomere model using MCell
Skeletal muscle contraction is initiated when an action potential triggers the release of Ca(2+) into the sarcomere in a process referred to as excitation-contraction coupling. The speed and scale of this process makes direct observation very challenging and invasive. To determine how the concentrat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424466/ https://www.ncbi.nlm.nih.gov/pubmed/30845143 http://dx.doi.org/10.1371/journal.pcbi.1006712 |