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Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
The deregulation of metabolism is a hallmark of aging. As such, changes in the expression of metabolic genes and the profiles of amino acid levels are features associated with aging animals. We previously reported that the levels of most amino acids decline with age in Caenorhabditis elegans (C. ele...
Autores principales: | Liu, Yasmine J., Janssens, Georges E., McIntyre, Rebecca L., Molenaars, Marte, Kamble, Rashmi, Gao, Arwen W., Jongejan, Aldo, van Weeghel, Michel, MacInnes, Alyson W., Houtkooper, Riekelt H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424468/ https://www.ncbi.nlm.nih.gov/pubmed/30845140 http://dx.doi.org/10.1371/journal.pgen.1007633 |
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