Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis

BACKGROUND: Eukaryotic cells can respond to diverse stimuli by converging at serine-51 phosphorylation on eukaryotic initiation factor 2 alpha (eIF2α) and activate the integrated stress response (ISR). This is a key step in translational control and must be tightly regulated; however, persistent eIF...

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Detalles Bibliográficos
Autores principales: Onat, Umut I., Yildirim, Asli D., Tufanli, Özlem, Çimen, Ismail, Kocatürk, Begüm, Veli, Zehra, Hamid, Syed M., Shimada, Kenichi, Chen, Shuang, Sin, Jon, Shah, Prediman K., Gottlieb, Roberta A., Arditi, Moshe, Erbay, Ebru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424590/
https://www.ncbi.nlm.nih.gov/pubmed/30871699
http://dx.doi.org/10.1016/j.jacc.2018.12.055

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