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The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function

Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-bin...

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Detalles Bibliográficos
Autores principales:	Sapir, Tamar, Segal, Michal, Grigoryan, Gayane, Hansson, Karin M., James, Peter, Segal, Menahem, Reiner, Orly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424868/ https://www.ncbi.nlm.nih.gov/pubmed/30918483 http://dx.doi.org/10.3389/fncel.2019.00092

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