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Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay

Aldehyde dehydrogenases (ALDHs) defend intracellular homeostasis by catalyzing the conversion of toxic aldehydes into non-toxic carboxylic acids, which is of particular importance to the self-renewal of stem cells and cancer stem cells. The widely used ALDEFLUOR assay was initially designed to indic...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Sheng, Dandan, Wang, Dong, Ma, Wei, Deng, Qiaodan, Deng, Lu, Liu, Suling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424948/
https://www.ncbi.nlm.nih.gov/pubmed/30220009
http://dx.doi.org/10.1007/s10565-018-9444-y