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Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases

We studied the inhibitory activity of methylene blue (MB) γ-carbolines (gC) conjugates (MB-gCs) against human erythrocyte acetylcholinesterase (AChE), equine serum butyrylcholinesterase (BChE), and a structurally related enzyme, porcine liver carboxylesterase (CaE). In addition, we determined the ab...

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Detalles Bibliográficos
Autores principales:	Bachurin, Sergey O., Makhaeva, Galina F., Shevtsova, Elena F., Boltneva, Natalia P., Kovaleva, Nadezhda V., Lushchekina, Sofya V., Rudakova, Elena V., Dubova, Ludmila G., Vinogradova, Daria V., Sokolov, Vladimir B., Aksinenko, Alexey Yu., Fisenko, Vladimir P., Richardson, Rudy J., Aliev, Gjumrakch
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424957/ https://www.ncbi.nlm.nih.gov/pubmed/30890752 http://dx.doi.org/10.1038/s41598-019-41272-4

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