Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer

Lung cancers are frequently characterized by inappropriate activation of epidermal growth factor receptor (EGFR)-dependent signaling and epigenetic silencing of the NADPH oxidase (NOX) enzyme DUOX1, both potentially contributing to worse prognosis. Based on previous findings linking DUOX1 with redox...

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Detalles Bibliográficos
Autores principales: Little, Andrew C., Hristova, Milena, van Lith, Loes, Schiffers, Caspar, Dustin, Christopher M., Habibovic, Aida, Danyal, Karamatullah, Heppner, David E., Lin, Miao-Chong J., van der Velden, Jos, Janssen-Heininger, Yvonne M., van der Vliet, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425021/
https://www.ncbi.nlm.nih.gov/pubmed/30890751
http://dx.doi.org/10.1038/s41598-019-41395-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425021/
https://www.ncbi.nlm.nih.gov/pubmed/30890751
http://dx.doi.org/10.1038/s41598-019-41395-8

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