Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

Dopamine (DA) release in striatum is functionally segregated across a dorsolateral/ventromedial axis. Interestingly, nigrostriatal DA signaling disruption in Parkinson’s disease (PD) preferentially affects the dorsolateral striatum. The relationship between afferent presynaptic calcium transients (P...

Descripción completa

Detalles Bibliográficos
Autores principales: Sgobio, Carmelo, Sun, Lixin, Ding, Jinhui, Herms, Jochen, Lovinger, David M., Cai, Huaibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425036/
https://www.ncbi.nlm.nih.gov/pubmed/30890737
http://dx.doi.org/10.1038/s41598-019-41091-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425036/
https://www.ncbi.nlm.nih.gov/pubmed/30890737
http://dx.doi.org/10.1038/s41598-019-41091-7

Ejemplares similares