Targeting Cytokine Signaling and Lymphocyte Traffic via Small Molecules in Inflammatory Bowel Disease: JAK Inhibitors and S1PR Agonists

The inflammatory Bowel diseases (IBDs) are a chronic, relapsing inflammatory diseases of the gastrointestinal tract with heterogeneous behavior and prognosis. The introduction of biological therapies including anti-TNF, anti-IL-12/23, and anti-integrins, has revolutionized the treatment of IBD, but...

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Detalles Bibliográficos
Autores principales: Pérez-Jeldres, Tamara, Tyler, Christopher J., Boyer, Joshua D., Karuppuchamy, Thangaraj, Yarur, Andrés, Giles, Daniel A., Yeasmin, Shaila, Lundborg, Luke, Sandborn, William J., Patel, Derek R., Rivera-Nieves, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425155/
https://www.ncbi.nlm.nih.gov/pubmed/30930775
http://dx.doi.org/10.3389/fphar.2019.00212

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