Cargando…

Minocycline impedes mitochondrial-dependent cell death and stabilizes expression of hypoxia inducible factor-1α in spinal cord injury

INTRODUCTION: One of the crucial mechanisms following spinal cord injury is mitochondria-associated cell death. Minocycline, an anti-inflammatory drug, is well known to impede mitochondrial cell death. However, there has been no study on the effect of minocycline linking Fas cell surface death recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Guolei, Zha, Junpu, Liu, Junchuan, Di, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2018
Materias:	Experimental Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425201/ https://www.ncbi.nlm.nih.gov/pubmed/30899301 http://dx.doi.org/10.5114/aoms.2018.73520

Ejemplares similares

Analysis of the Effect of Posterior Lateral Malleolus Plate Fixation on the Curative Effect and Mechanical Stability of Complex Ankle Fractures
por: Zha, Junpu, et al.
Publicado: (2022)

Use of Intravenous Paracetamol Preoperatively Favors Lower Risk of Delirium and Functional Recovery in Elderly Patients with Hip Fracture: A Propensity Score-Matched Analysis
por: Guo, Junfei, et al.
Publicado: (2022)

Minocycline prevents hypoxia-induced seizures
por: Fukushi, Isato, et al.
Publicado: (2023)

Super elderly patients with intertrochanteric fractures do not predict worse outcomes and higher mortality than elderly patients: a propensity score matched analysis
por: Guo, Junfei, et al.
Publicado: (2020)

Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury
por: Shultz, Robert B., et al.
Publicado: (2017)

Hypoxia-Inducible Factor 1α (HIF-1α) Counteracts the Acute Death of Cells Transplanted into the Injured Spinal Cord
por: David, Brian T., et al.
Publicado: (2020)

Minocycline-Loaded Poly(α-Lipoic Acid)–Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury
por: Lin, Feng, et al.
Publicado: (2022)

Use of a Minimally Invasive Traction Repositor versus Conventional Manual Traction for the Treatment of Tibial Fractures: A Comparative Study from a Tertiary Hospital in China
por: Zha, Junpu, et al.
Publicado: (2022)

LncRNA expression in the spinal cord modulated by minocycline in a mouse model of spared nerve injury
por: Liu, Zihao, et al.
Publicado: (2017)

Prevention of hypoglycemia-induced neuronal death by minocycline
por: Won, Seok Joon, et al.
Publicado: (2012)

Minocycline delayed photoreceptor death in the rds mice through iNOS-dependent mechanism
por: Yang, Li-ping, et al.
Publicado: (2007)

Prolonged Minocycline Treatment Impairs Motor Neuronal Survival and Glial Function in Organotypic Rat Spinal Cord Cultures
por: Pinkernelle, Josephine, et al.
Publicado: (2013)

A role for spinal cord hypoxia in neurodegeneration
por: Hernandez-Gerez, Elena, et al.
Publicado: (2019)

Minocycline Enhance the Restorative Ability of Olfactory Ensheathing Cells by the Upregulation of BDNF and GDNF Expression After Spinal Cord Injury
por: Pourkhodadad, Soheila, et al.
Publicado: (2021)

Selected gene profiles of stressed NSC-34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatment
por: KEILHOFF, GERBURG, et al.
Publicado: (2016)

Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells
por: Turcotte, M L, et al.
Publicado: (2002)

Involvement of the Spinal Cord in Mitochondrial Disorders
por: Finsterer, Josef, et al.
Publicado: (2018)

Minocycline-Suppression of Early Peripheral Inflammation Reduces Hypoxia-Induced Neonatal Brain Injury
por: Min, Yingjun, et al.
Publicado: (2017)

Neuroprotective Effects of Combined Treatment with Minocycline and Olfactory Ensheathing Cells Transplantation against Inflammation and Oxidative Stress after Spinal Cord Injury
por: Pourkhodadad, Soheila, et al.
Publicado: (2019)

Effect of General vs. Regional Anesthesia on Mortality, Complications, and Prognosis in Older Adults Undergoing Hip Fracture Surgery: A Propensity-Score-Matched Cohort Analysis
por: Zhang, Guolei, et al.
Publicado: (2022)

CELL DEATH IN THE EMBRYONIC CHICK SPINAL CORD
por: O'Connor, Thomas M., et al.
Publicado: (1974)

Minocycline attenuates interferon-α-induced impairments in rat fear extinction
por: Bi, Qiang, et al.
Publicado: (2016)

Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets
por: van Gisbergen, Marike W., et al.
Publicado: (2020)

Restoring mitochondrial cardiolipin homeostasis reduces cell death and promotes recovery after spinal cord injury
por: Liu, Nai-Kui, et al.
Publicado: (2022)

Minocycline-induced hyperpigmentation
por: Fiscus, Valena, et al.
Publicado: (2014)

Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats
por: Hsieh, Ming-Chun, et al.
Publicado: (2018)

Mapping of neuroinflammation-induced hypoxia in the spinal cord using optoacoustic imaging
por: Ramos-Vega, Marta, et al.
Publicado: (2022)

Alterations in Localized Electrical Impedance Myography of Biceps Brachii Muscles Paralyzed by Spinal Cord Injury
por: Li, Le, et al.
Publicado: (2017)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

Minocycline Alleviates Cluster Formation of Activated Microglia and Age-dependent Dopaminergic Cell Death in the Substantia Nigra of Zitter Mutant Rat
por: Taguchi, Daisuke, et al.
Publicado: (2020)

Minocycline hydrochloride nanoliposomes inhibit the production of TNF-α in LPS-stimulated macrophages
por: Liu, D, et al.
Publicado: (2012)

Case of Death from Division of the Spinal Cord in the Neck
por: Baillie, N. B.
Publicado: (1873)

Diallyl trisulfide improves spinal cord ischemia–reperfusion injury damage by activating AMPK to stabilize mitochondrial function
por: Sun, Yang, et al.
Publicado: (2023)

Stability of Predictors of Mortality after Spinal Cord Injury
por: Krause, James S., et al.
Publicado: (2012)

Spinal cord injuries - Instability is the issue-stabilization is the treatment
por: Goel, Atul
Publicado: (2022)

Skeletal muscle mitochondrial health and spinal cord injury
por: O’Brien, Laura C, et al.
Publicado: (2016)

Temporal modifications in bone following spinal cord injury in rats
por: Medalha, Carla Christina, et al.
Publicado: (2012)

Minocycline prevents primary duck neurons from duck Tembusu virus-induced death
por: KULPRASERTSRI, Sittinee, et al.
Publicado: (2021)

HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia
por: Laquatra, Claudio, et al.
Publicado: (2021)

Novel oxygen sensing mechanism in the spinal cord involved in cardiorespiratory responses to hypoxia
por: Barioni, Nicole O., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u95t9gm1gqkubsbsrp6b9bnvaa