MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients

INTRODUCTION: TP53 and MGMT alterations play a crucial role in glioblastoma (GB) pathogenesis. TP53 and MGMT function is affected by several pathologic mechanisms, such as point mutations or promoter methylation, which are well characterized. Expression of both genes can be regulated by other mechan...

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Detalles Bibliográficos
Autores principales: Jesionek-Kupnicka, Dorota, Braun, Marcin, Trąbska-Kluch, Berenika, Czech, Joanna, Szybka, Małgorzata, Szymańska, Bożena, Kulczycka-Wojdala, Dominika, Bieńkowski, Michał, Kordek, Radzisław, Zawlik, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425218/
https://www.ncbi.nlm.nih.gov/pubmed/30899304
http://dx.doi.org/10.5114/aoms.2017.69374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425218/
https://www.ncbi.nlm.nih.gov/pubmed/30899304
http://dx.doi.org/10.5114/aoms.2017.69374

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