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Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis
Continuous veno-venous hemofiltration (CVVH) in the treatment of severe acute pancreatitis (SAP) was investigated. A total of 60 patients with SAP treated in Affiliated Dongtai Hospital of Nantong University from October 2015 to October 2017 were enrolled in this retrospective study. Among them, 32...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425253/ https://www.ncbi.nlm.nih.gov/pubmed/30906462 http://dx.doi.org/10.3892/etm.2019.7246 |
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author | Chen, Xuan Sun, Meifang Mao, Xiuhong Liu, Xiaoxia Sun, Weihe |
author_facet | Chen, Xuan Sun, Meifang Mao, Xiuhong Liu, Xiaoxia Sun, Weihe |
author_sort | Chen, Xuan |
collection | PubMed |
description | Continuous veno-venous hemofiltration (CVVH) in the treatment of severe acute pancreatitis (SAP) was investigated. A total of 60 patients with SAP treated in Affiliated Dongtai Hospital of Nantong University from October 2015 to October 2017 were enrolled in this retrospective study. Among them, 32 patients received CVVH and routine internal medicine therapy (the CVVH group), and 28 received routine internal medicine therapy (the control group). Then biochemical indexes and severity of SAP after treatment were detected to investigate the roles of CVVH and routine internal medicine therapy in treating SAP. Inflammatory factors in both the CVVH and control groups were significantly decreased after treatment (P<0.05), and CVVH could eliminate more factors. Comparison of blood biochemical indexes between the CVVH and control groups were carried out. Significant improvement was found (P<0.05) after CVVH and routine internal medicine therapy. Besides, Acute Physiology and Chronic Health Evaluation (APACHE)-II grade was significantly decreased in the CVVH group compared with that in the control group after 7 days. CVVH therapy can effectively reduce the levels of inflammatory factors in SAP patients, improve their biochemical and physiological indicators, and have high clinical application value. |
format | Online Article Text |
id | pubmed-6425253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-64252532019-03-22 Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis Chen, Xuan Sun, Meifang Mao, Xiuhong Liu, Xiaoxia Sun, Weihe Exp Ther Med Articles Continuous veno-venous hemofiltration (CVVH) in the treatment of severe acute pancreatitis (SAP) was investigated. A total of 60 patients with SAP treated in Affiliated Dongtai Hospital of Nantong University from October 2015 to October 2017 were enrolled in this retrospective study. Among them, 32 patients received CVVH and routine internal medicine therapy (the CVVH group), and 28 received routine internal medicine therapy (the control group). Then biochemical indexes and severity of SAP after treatment were detected to investigate the roles of CVVH and routine internal medicine therapy in treating SAP. Inflammatory factors in both the CVVH and control groups were significantly decreased after treatment (P<0.05), and CVVH could eliminate more factors. Comparison of blood biochemical indexes between the CVVH and control groups were carried out. Significant improvement was found (P<0.05) after CVVH and routine internal medicine therapy. Besides, Acute Physiology and Chronic Health Evaluation (APACHE)-II grade was significantly decreased in the CVVH group compared with that in the control group after 7 days. CVVH therapy can effectively reduce the levels of inflammatory factors in SAP patients, improve their biochemical and physiological indicators, and have high clinical application value. D.A. Spandidos 2019-04 2019-02-06 /pmc/articles/PMC6425253/ /pubmed/30906462 http://dx.doi.org/10.3892/etm.2019.7246 Text en Copyright: © Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Chen, Xuan Sun, Meifang Mao, Xiuhong Liu, Xiaoxia Sun, Weihe Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title | Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title_full | Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title_fullStr | Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title_full_unstemmed | Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title_short | Effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
title_sort | effectiveness of continuous veno-venous hemofiltration in the treatment of severe acute pancreatitis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425253/ https://www.ncbi.nlm.nih.gov/pubmed/30906462 http://dx.doi.org/10.3892/etm.2019.7246 |
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