Islet Transplantation: Growing Trans‐Species Islets in Tumor Extract‐Remodeled Testicles (Adv. Sci. 6/2019)

In article number 1801694, Junfeng Zhang, Chunming Wang, Lei Dong, and co‐workers biochemically remodel one of the two testicles of a mouse into a site that can protect xenogeneic islet cells from immune rejection. The transplants, both of primary origin and from a cancer source, can grow and functi...

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Detalles Bibliográficos
Autores principales: Wang, Zhenzhen, Rui, Xiaying, Qiu, Junni, Yan, Yiqing, Gan, Jingjing, Liu, Shang, Wang, Lintao, Zhang, Junfeng, Wang, Chunming, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425430/
http://dx.doi.org/10.1002/advs.201970036
Descripción
Sumario:In article number 1801694, Junfeng Zhang, Chunming Wang, Lei Dong, and co‐workers biochemically remodel one of the two testicles of a mouse into a site that can protect xenogeneic islet cells from immune rejection. The transplants, both of primary origin and from a cancer source, can grow and function like a normal islet in the new host body, thus compensating for the glucose‐control function of the incapable pancreas. [Image: see text]

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