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The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge

In rodents, the preovulatory LH surge is temporally gated, but the timing cue is unknown. Estrogen primes neurons in the anteroventral periventricular nucleus (AVPV) to secrete kisspeptin, which potently activates GnRH neurons to release GnRH, eliciting a surge of LH to induce ovulation. Deletion of...

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Detalles Bibliográficos
Autores principales:	Tonsfeldt, Karen J, Schoeller, Erica L, Brusman, Liza E, Cui, Laura J, Lee, Jinkwon, Mellon, Pamela L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425515/ https://www.ncbi.nlm.nih.gov/pubmed/30906911 http://dx.doi.org/10.1210/js.2018-00228

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