Cargando…

LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation

BACKGROUND: Long non-coding RNAs (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 in atrial fibrosis remains undefined. This study aims to elucidate the pathophysiological role of lncRNA PVT1 in the regulation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Feng, Li, Zhe, Ding, Wen-mao, Yan, Ling, Zhao, Qing-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425687/
https://www.ncbi.nlm.nih.gov/pubmed/30894138
http://dx.doi.org/10.1186/s10020-019-0074-5