Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury

Mechanical stress and hypoxia during episodes of ocular hypertension (OHT) trigger glial activation and neuroinflammation in the retina. Glial activation and release of pro-inflammatory cytokines TNFα and IL-1β, complement, and other danger factors was shown to facilitate injury and loss of retinal...

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Detalles Bibliográficos
Autores principales: Pronin, Alexey, Pham, Dien, An, Weijun, Dvoriantchikova, Galina, Reshetnikova, Galina, Qiao, Jianzhong, Kozhekbaeva, Zhanna, Reiser, Ashlyn E., Slepak, Vladlen Z., Shestopalov, Valery I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425693/
https://www.ncbi.nlm.nih.gov/pubmed/30930743
http://dx.doi.org/10.3389/fnmol.2019.00036

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