Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families

The risk for autoimmunity and subsequently type 1 diabetes is 10-fold higher in children with a first-degree family history of type 1 diabetes (FDR children) than in children in the general population (GP children). We analyzed children with high-risk HLA genotypes (n = 4,573) in the longitudinal TE...

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Detalles Bibliográficos
Autores principales: Hippich, Markus, Beyerlein, Andreas, Hagopian, William A., Krischer, Jeffrey P., Vehik, Kendra, Knoop, Jan, Winker, Christiane, Toppari, Jorma, Lernmark, Åke, Rewers, Marian J., Steck, Andrea K., She, Jin-Xiong, Akolkar, Beena, Robertson, Catherine C., Onengut-Gumuscu, Suna, Rich, Stephen S., Bonifacio, Ezio, Ziegler, Anette-G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425872/
https://www.ncbi.nlm.nih.gov/pubmed/30655385
http://dx.doi.org/10.2337/db18-0882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425872/
https://www.ncbi.nlm.nih.gov/pubmed/30655385
http://dx.doi.org/10.2337/db18-0882

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