Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis

Proximal tubular epithelial cells are highly energy demanding. Their energy need is covered mostly from mitochondrial fatty acid oxidation. Whether derailments in fatty acid metabolism and mitochondrial dysfunction are forerunners of tubular damage has been suggested but is not entirely clear. Here...

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Detalles Bibliográficos
Autores principales: Kruger, Claudia, Nguyen, Trang-Tiffany, Breaux, Chelsea, Guillory, Alana, Mangelli, Margaret, Fridianto, Kevin T., Kovalik, Jean-Paul, Burk, David H., Noland, Robert C., Mynatt, Randall, Stadler, Krisztian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425873/
https://www.ncbi.nlm.nih.gov/pubmed/30728184
http://dx.doi.org/10.2337/db18-0090

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