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Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR

Growing evidence indicate that large antigen-containing particles induce potent T cell-dependent high-affinity antibody responses. These responses require large particle internalization after recognition by the B cell receptor (BCR) on B cells. However, the molecular mechanisms governing BCR-mediate...

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Detalles Bibliográficos
Autores principales:	Verstegen, Niels J. M., Unger, Peter-Paul A., Walker, Julia Z., Nicolet, Benoit P., Jorritsma, Tineke, van Rijssel, Jos, Spaapen, Robbert M., de Wit, Jelle, van Buul, Jaap D., ten Brinke, Anja, van Ham, S. Marieke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425997/ https://www.ncbi.nlm.nih.gov/pubmed/30930895 http://dx.doi.org/10.3389/fimmu.2019.00415

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