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IL-27 Receptor Signaling on T cells Augments GVHD Severity through Enhancing Th1 Responses

IL-27 is a heterodimeric cytokine comprised of IL-27p28 and EBI3. As a relatively new member of the IL-12 family, the biological mechanisms associated with the role of IL-27 in the immune response are ambiguous, displaying both proinflammatory and suppressive functions that seem to be dependent on t...

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Detalles Bibliográficos
Autores principales: Bastian, David, Liu, Yuejun, Wu, Yongxia, Schutt, Steven, Nguyen, Hung D., Daenthanasanmak, Anusara, Sofi, M.Hanief, Zhang, Mengmeng, Iamsuwat, Supinya, Yu, Xue-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426137/
https://www.ncbi.nlm.nih.gov/pubmed/30906912