FXR agonism protects against liver injury in a rat model of intestinal failure-associated liver disease

BACKGROUND: Intestinal failure-associated liver disease (IFALD) is a clinical challenge. The pathophysiol-ogy is multifactorial and remains poorly understood. Disturbed recirculation of bile salts, e.g. due to loss of bile via an enterocutaneous fistula, is considered a major contributing factor. We...

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Detalles Bibliográficos
Autores principales: Koelfat, Kiran V.K., Visschers, Ruben G.J., Hodin, Caroline M.J.M., de Waart, D. Rudi, van Gemert, Wim G., Cleutjens, Jack P.M., Gijbels, Marion J., Shiri-Sverdlov, Ronit, Mookerjee, Rajeshwar P., Lenaerts, Kaatje, Schaap, Frank G., Steven W.M., Olde Damink
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426251/
https://www.ncbi.nlm.nih.gov/pubmed/30895273

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