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OptRAM: In-silico strain design via integrative regulatory-metabolic network modeling
The ultimate goal of metabolic engineering is to produce desired compounds on an industrial scale in a cost effective manner. To address challenges in metabolic engineering, computational strain optimization algorithms based on genome-scale metabolic models have increasingly been used to aid in over...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426274/ https://www.ncbi.nlm.nih.gov/pubmed/30849073 http://dx.doi.org/10.1371/journal.pcbi.1006835 |