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UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond
Nonsense-mediated mRNA decay (NMD), which is arguably the best-characterized translation-dependent regulatory pathway in mammals, selectively degrades mRNAs as a means of post-transcriptional gene control. Control can be for the purpose of ensuring the quality of gene expression. Alternatively, cont...
Autores principales: | Kim, Yoon Ki, Maquat, Lynne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426291/ https://www.ncbi.nlm.nih.gov/pubmed/30655309 http://dx.doi.org/10.1261/rna.070136.118 |
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