Point-of-care HIV RNA testing and immediate antiretroviral therapy initiation in young adults seeking out-patient care in Kenya

We evaluated outcomes of an HIV-1-testing intervention using rapid HIV tests followed by point-of-care Xpert Qual testing for HIV-1 RNA. Of 706 young urgent-care seeking participants evaluated, 24 (3.4%) had chronic HIV (antibody-positive), 3 (0.4%) acute HIV-1 (Qual-positive, antibody-negative), an...

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Detalles Bibliográficos
Autores principales: Sanders, Eduard J., Chirro, Oscar, Oduor, Clifford, Mangi, Juma, Wahome, Elizabeth, Price, Matthew A., Gelderblom, Hubert C., van der Elst, Elisabeth M., Graham, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426340/
https://www.ncbi.nlm.nih.gov/pubmed/30882493
http://dx.doi.org/10.1097/QAD.0000000000002110
Descripción
Sumario:We evaluated outcomes of an HIV-1-testing intervention using rapid HIV tests followed by point-of-care Xpert Qual testing for HIV-1 RNA. Of 706 young urgent-care seeking participants evaluated, 24 (3.4%) had chronic HIV (antibody-positive), 3 (0.4%) acute HIV-1 (Qual-positive, antibody-negative), and 3 (0.4%) early HIV-1 infection (Qual-positive, antibody-discordant). Overall, 21 (70.0%) diagnosed patients started antiretroviral therapy after a median of 4 days (range 0–71). HIV-1 RNA testing led to an increase in confirmed diagnoses by 25%.

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