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Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study
OBJECTIVE: To investigate immunostimulatory effects of acetylsalicylic acid during experimental human endotoxemia and in sepsis patients. DESIGN: Double-blind, randomized, placebo-controlled study in healthy volunteers and ex vivo stimulation experiments using monocytes of septic patients. SETTING:...
Autores principales: | Leijte, Guus P., Kiers, Dorien, van der Heijden, Wouter, Jansen, Aron, Gerretsen, Jelle, Boerrigter, Verin, Netea, Mihai G., Kox, Matthijs, Pickkers, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426341/ https://www.ncbi.nlm.nih.gov/pubmed/30585832 http://dx.doi.org/10.1097/CCM.0000000000003630 |
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