Cargando…
Ganciclovir Therapeutic Drug Monitoring: A Case Series
This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the t...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Therapeutic Drug Monitoring
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426343/ https://www.ncbi.nlm.nih.gov/pubmed/30883503 http://dx.doi.org/10.1097/FTD.0000000000000598 |
_version_ | 1783404989289332736 |
---|---|
author | Märtson, Anne-Grete Touw, Daan Damman, Kevin Bakker, Martijn Oude Lansink-Hartgring, Annemieke van der Werf, Tjip Knoester, Marjolein Alffenaar, Jan-Willem C. |
author_facet | Märtson, Anne-Grete Touw, Daan Damman, Kevin Bakker, Martijn Oude Lansink-Hartgring, Annemieke van der Werf, Tjip Knoester, Marjolein Alffenaar, Jan-Willem C. |
author_sort | Märtson, Anne-Grete |
collection | PubMed |
description | This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the third is an HIV-positive patient. These patients were all diagnosed with cytomegalovirus and treated with ganciclovir. Our case studies illustrate how therapeutic drug monitoring–guided dosing can be helpful in the management of these complex cases. |
format | Online Article Text |
id | pubmed-6426343 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Therapeutic Drug Monitoring |
record_format | MEDLINE/PubMed |
spelling | pubmed-64263432019-04-15 Ganciclovir Therapeutic Drug Monitoring: A Case Series Märtson, Anne-Grete Touw, Daan Damman, Kevin Bakker, Martijn Oude Lansink-Hartgring, Annemieke van der Werf, Tjip Knoester, Marjolein Alffenaar, Jan-Willem C. Ther Drug Monit Grand Rounds This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the third is an HIV-positive patient. These patients were all diagnosed with cytomegalovirus and treated with ganciclovir. Our case studies illustrate how therapeutic drug monitoring–guided dosing can be helpful in the management of these complex cases. Therapeutic Drug Monitoring 2019-04 2019-01-28 /pmc/articles/PMC6426343/ /pubmed/30883503 http://dx.doi.org/10.1097/FTD.0000000000000598 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Grand Rounds Märtson, Anne-Grete Touw, Daan Damman, Kevin Bakker, Martijn Oude Lansink-Hartgring, Annemieke van der Werf, Tjip Knoester, Marjolein Alffenaar, Jan-Willem C. Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title | Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title_full | Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title_fullStr | Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title_full_unstemmed | Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title_short | Ganciclovir Therapeutic Drug Monitoring: A Case Series |
title_sort | ganciclovir therapeutic drug monitoring: a case series |
topic | Grand Rounds |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426343/ https://www.ncbi.nlm.nih.gov/pubmed/30883503 http://dx.doi.org/10.1097/FTD.0000000000000598 |
work_keys_str_mv | AT martsonannegrete ganciclovirtherapeuticdrugmonitoringacaseseries AT touwdaan ganciclovirtherapeuticdrugmonitoringacaseseries AT dammankevin ganciclovirtherapeuticdrugmonitoringacaseseries AT bakkermartijn ganciclovirtherapeuticdrugmonitoringacaseseries AT oudelansinkhartgringannemieke ganciclovirtherapeuticdrugmonitoringacaseseries AT vanderwerftjip ganciclovirtherapeuticdrugmonitoringacaseseries AT knoestermarjolein ganciclovirtherapeuticdrugmonitoringacaseseries AT alffenaarjanwillemc ganciclovirtherapeuticdrugmonitoringacaseseries |