Cargando…

Ganciclovir Therapeutic Drug Monitoring: A Case Series

This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the t...

Descripción completa

Detalles Bibliográficos
Autores principales: Märtson, Anne-Grete, Touw, Daan, Damman, Kevin, Bakker, Martijn, Oude Lansink-Hartgring, Annemieke, van der Werf, Tjip, Knoester, Marjolein, Alffenaar, Jan-Willem C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426343/
https://www.ncbi.nlm.nih.gov/pubmed/30883503
http://dx.doi.org/10.1097/FTD.0000000000000598
_version_ 1783404989289332736
author Märtson, Anne-Grete
Touw, Daan
Damman, Kevin
Bakker, Martijn
Oude Lansink-Hartgring, Annemieke
van der Werf, Tjip
Knoester, Marjolein
Alffenaar, Jan-Willem C.
author_facet Märtson, Anne-Grete
Touw, Daan
Damman, Kevin
Bakker, Martijn
Oude Lansink-Hartgring, Annemieke
van der Werf, Tjip
Knoester, Marjolein
Alffenaar, Jan-Willem C.
author_sort Märtson, Anne-Grete
collection PubMed
description This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the third is an HIV-positive patient. These patients were all diagnosed with cytomegalovirus and treated with ganciclovir. Our case studies illustrate how therapeutic drug monitoring–guided dosing can be helpful in the management of these complex cases.
format Online
Article
Text
id pubmed-6426343
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Therapeutic Drug Monitoring
record_format MEDLINE/PubMed
spelling pubmed-64263432019-04-15 Ganciclovir Therapeutic Drug Monitoring: A Case Series Märtson, Anne-Grete Touw, Daan Damman, Kevin Bakker, Martijn Oude Lansink-Hartgring, Annemieke van der Werf, Tjip Knoester, Marjolein Alffenaar, Jan-Willem C. Ther Drug Monit Grand Rounds This article presents 3 cases of immunocompromised patients for whom therapeutic drug monitoring of ganciclovir in combination with cytomegalovirus viral load measurement was used to guide treatment. The first patient is diagnosed with thymoma A, the second is a heart transplant recipient, and the third is an HIV-positive patient. These patients were all diagnosed with cytomegalovirus and treated with ganciclovir. Our case studies illustrate how therapeutic drug monitoring–guided dosing can be helpful in the management of these complex cases. Therapeutic Drug Monitoring 2019-04 2019-01-28 /pmc/articles/PMC6426343/ /pubmed/30883503 http://dx.doi.org/10.1097/FTD.0000000000000598 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Grand Rounds
Märtson, Anne-Grete
Touw, Daan
Damman, Kevin
Bakker, Martijn
Oude Lansink-Hartgring, Annemieke
van der Werf, Tjip
Knoester, Marjolein
Alffenaar, Jan-Willem C.
Ganciclovir Therapeutic Drug Monitoring: A Case Series
title Ganciclovir Therapeutic Drug Monitoring: A Case Series
title_full Ganciclovir Therapeutic Drug Monitoring: A Case Series
title_fullStr Ganciclovir Therapeutic Drug Monitoring: A Case Series
title_full_unstemmed Ganciclovir Therapeutic Drug Monitoring: A Case Series
title_short Ganciclovir Therapeutic Drug Monitoring: A Case Series
title_sort ganciclovir therapeutic drug monitoring: a case series
topic Grand Rounds
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426343/
https://www.ncbi.nlm.nih.gov/pubmed/30883503
http://dx.doi.org/10.1097/FTD.0000000000000598
work_keys_str_mv AT martsonannegrete ganciclovirtherapeuticdrugmonitoringacaseseries
AT touwdaan ganciclovirtherapeuticdrugmonitoringacaseseries
AT dammankevin ganciclovirtherapeuticdrugmonitoringacaseseries
AT bakkermartijn ganciclovirtherapeuticdrugmonitoringacaseseries
AT oudelansinkhartgringannemieke ganciclovirtherapeuticdrugmonitoringacaseseries
AT vanderwerftjip ganciclovirtherapeuticdrugmonitoringacaseseries
AT knoestermarjolein ganciclovirtherapeuticdrugmonitoringacaseseries
AT alffenaarjanwillemc ganciclovirtherapeuticdrugmonitoringacaseseries