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Interaction of the Human Papillomavirus E1 Helicase with UAF1-USP1 Promotes Unidirectional Theta Replication of Viral Genomes

Human papillomaviruses (HPVs) are important pathogens with a significant medical burden. HPV genomes replicate in infected cells via bidirectional theta replication and a poorly understood unidirectional mechanism. In this report, we provide evidence that the previously described interaction between...

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Detalles Bibliográficos
Autores principales: Orav, Marit, Gagnon, David, Archambault, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426595/
https://www.ncbi.nlm.nih.gov/pubmed/30890612
http://dx.doi.org/10.1128/mBio.00152-19