Cargando…

AP-2-Dependent Endocytic Recycling of the Chitin Synthase Chs3 Regulates Polarized Growth in Candida albicans

The human fungal pathogen Candida albicans is known to require endocytosis to enable its adaptation to diverse niches and to maintain its highly polarized hyphal growth phase. While studies have identified changes in transcription leading to the synthesis and secretion of new proteins to facilitate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knafler, H. C., Smaczynska-de Rooij, I. I., Walker, L. A., Lee, K. K., Gow, N. A. R., Ayscough, K. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426607/ https://www.ncbi.nlm.nih.gov/pubmed/30890602 http://dx.doi.org/10.1128/mBio.02421-18

Ejemplares similares

Yeast Endocytic Adaptor AP-2 Binds the Stress Sensor Mid2 and Functions in Polarized Cell Responses
por: Chapa-y-Lazo, Bernardo, et al.
Publicado: (2014)

Dissection of the Candida albicans class I chitin synthase promoters
por: Lenardon, Megan D., et al.
Publicado: (2009)

An Abp1-Dependent Route of Endocytosis Functions when the Classical Endocytic Pathway in Yeast Is Inhibited
por: Aghamohammadzadeh, Soheil, et al.
Publicado: (2014)

Cell wall protection by the Candida albicans class I chitin synthases
por: Preechasuth, Kanya, et al.
Publicado: (2015)

Individual chitin synthase enzymes synthesize microfibrils of differing structure at specific locations in the Candida albicans cell wall
por: Lenardon, Megan D, et al.
Publicado: (2007)

The Glucan-Remodeling Enzyme Phr1p and the Chitin Synthase Chs1p Cooperate to Maintain Proper Nuclear Segregation and Cell Integrity in Candida albicans
por: Degani, Genny, et al.
Publicado: (2019)

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies
por: Walker, Louise A., et al.
Publicado: (2015)

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins
por: Walker, Louise A., et al.
Publicado: (2008)

Phosphorylation Regulates the Endocytic Function of the Yeast Dynamin-Related Protein Vps1
por: Smaczynska-de Rooij, Iwona I., et al.
Publicado: (2016)

A Charge Swap mutation E461K in the yeast dynamin Vps1 reduces endocytic invagination
por: Palmer, Sarah E, et al.
Publicado: (2015)

Targeting of Chitin Synthase 3 to Polarized Growth Sites in Yeast Requires Chs5p and Myo2p
por: Santos, Beatriz, et al.
Publicado: (1997)

Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans
por: da Silva Dantas, Alessandra, et al.
Publicado: (2021)

The complex interactions of Chs5p, the ChAPs, and the cargo Chs3p
por: Rockenbauch, Uli, et al.
Publicado: (2012)

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions
por: Wagener, Jeanette, et al.
Publicado: (2017)

Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast
por: Oh, Younghoon, et al.
Publicado: (2012)

The chitin synthase FgChs2 and other FgChss co-regulate vegetative development and virulence in F. graminearum
por: Liu, Zunyong, et al.
Publicado: (2016)

Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites
por: Chapa-y-Lazo, Bernardo, et al.
Publicado: (2014)

RNAi-Mediated Knockdown of Chitin Synthase 1 (CHS1) Gene Causes Mortality and Decreased Longevity and Fecundity in Aphis gossypii
por: Ullah, Farman, et al.
Publicado: (2019)

Identification of annotation artifacts concerning the chalcone synthase (CHS)
por: Bartas, Martin, et al.
Publicado: (2023)

Differential trafficking and timed localization of two chitin synthase proteins, Chs2p and Chs3p [published erratum appears in J Cell Biol 1996 Dec;135(6 Pt 2):1925]
Publicado: (1996)

Impact of low lethal concentrations of buprofezin on biological traits and expression profile of chitin synthase 1 gene (CHS1) in melon aphid, Aphis gossypii
por: Ullah, Farman, et al.
Publicado: (2019)

Insights into dynamin-associated disorders through analysis of equivalent mutations in the yeast dynamin Vps1
por: Moustaq, Laila, et al.
Publicado: (2016)

Phosphorylation of the WH2 domain in yeast Las17/WASP regulates G-actin binding and protein function during endocytosis
por: Tyler, J. J., et al.
Publicado: (2021)

Metabolic fitness of Candida albicans is indispensable for functional drug efflux, ergosterol, and chitin biosynthesis
por: Hans, Sandeep, et al.
Publicado: (2020)

Elucidating Key Motifs Required for Arp2/3-Dependent and Independent Actin Nucleation by Las17/WASP
por: Allwood, Ellen G., et al.
Publicado: (2016)

Mutation of key lysine residues in the Insert B region of the yeast dynamin Vps1 disrupts lipid binding and causes defects in endocytosis
por: Smaczynska-de Rooij, Iwona I., et al.
Publicado: (2019)

Author Correction: Impact of low lethal concentrations of buprofezin on biological traits and expression profile of chitin synthase 1 gene (CHS1) in melon aphid, Aphis gossypii
por: Ullah, Farman, et al.
Publicado: (2020)

ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in Aspergillus niger
por: Zhu, Yunqi, et al.
Publicado: (2023)

Cell biology of Candida albicans–host interactions
por: da Silva Dantas, Alessandra, et al.
Publicado: (2016)

Clonal evolution of Candida albicans, Candida glabrata and Candida dubliniensis at oral niche level in health and disease
por: Moorhouse, Alexander J., et al.
Publicado: (2021)

Differential gene expression signatures for cell wall integrity found in chitin synthase II (chs2Δ) and myosin II (myo1Δ) deficient cytokinesis mutants of Saccharomyces cerevisiae
por: Rodríguez-Quiñones, José F, et al.
Publicado: (2009)

Mapping the Substrate-Binding Sites in the Phosphatidylserine Synthase in Candida albicans
por: Zhou, Yue, et al.
Publicado: (2021)

A new toolkit for gene tagging in Candida albicans containing recyclable markers
por: Dueñas-Santero, Encarnación, et al.
Publicado: (2019)

Interactions between the Yeast SM22 Homologue Scp1 and Actin Demonstrate the Importance of Actin Bundling in Endocytosis
por: Gheorghe, Dana M., et al.
Publicado: (2008)

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition
por: Mukaremera, Liliane, et al.
Publicado: (2017)

Macrophage Migration Is Impaired within Candida albicans Biofilms
por: Alonso, Maria F., et al.
Publicado: (2017)

Endocytic recycling via the TGN underlies the polarized hyphal mode of life
por: Hernández-González, Miguel, et al.
Publicado: (2018)

Mannosylation in Candida albicans: role in cell wall function and immune recognition
por: Hall, Rebecca A., et al.
Publicado: (2013)

Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
por: Shahi, Garima, et al.
Publicado: (2022)

Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses
por: Alanazi, Humidah, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lomg70k06plmaq9ila60vtqk7t