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Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8(+) T Cell Families
After antigen stimulation cognate naïve CD8(+) T cells undergo rapid proliferation and ultimately their progeny differentiates into short-lived effectors and longer-lived memory T cells. Although the expansion of individual cells is very heterogeneous, the kinetics are reproducible at the level of t...
Autores principales: | Pandit, Aridaman, De Boer, Rob J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426761/ https://www.ncbi.nlm.nih.gov/pubmed/30923522 http://dx.doi.org/10.3389/fimmu.2019.00436 |
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