Cargando…

Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells

Pancreatic cancer has the worst prognosis among major malignancies, largely due to its highly invasive property and difficulty in early detection. Mechanistic insights into cancerous transformation and especially metastatic progression are imperative for developing novel treatment strategies. The ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Huhehasi, Hasan, Rokib, Zhang, Haitao, Gray, Joshua, Williams, Dominic, Miller, Morgan, Allen, Faith, Lee, Virlan, Kelly, Thomas, Zhou, Guo-Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426867/ https://www.ncbi.nlm.nih.gov/pubmed/30894654 http://dx.doi.org/10.1038/s41598-019-41346-3

Ejemplares similares

The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell Signals
por: Hasan, Rokib, et al.
Publicado: (2019)

PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins
por: Santio, Niina M., et al.
Publicado: (2020)

Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons
por: Schneider, Felix, et al.
Publicado: (2021)

CAP1 (Cyclase-Associated Protein 1) Exerts Distinct Functions in the Proliferation and Metastatic Potential of Breast Cancer Cells Mediated by ERK
por: Zhang, Haitao, et al.
Publicado: (2016)

miRNA mediated downregulation of cyclase-associated protein 1 (CAP1) is required for myoblast fusion
por: Singh, Anurag Kumar, et al.
Publicado: (2022)

Regulation of soluble guanylyl cyclase by phosphorylation
por: Zhou, Zongmin, et al.
Publicado: (2009)

Regulation of soluble guanylyl cyclase by phosphorylation
por: Zhou, Zongmin, et al.
Publicado: (2009)

The Cyclase-Associated Protein Cap1 Is Important for Proper Regulation of Infection-Related Morphogenesis in Magnaporthe oryzae
por: Zhou, Xiaoying, et al.
Publicado: (2012)

The Role of Soluble Adenylyl Cyclase in the Regulation of Flagellar Motility in Ascidian Sperm
por: Shiba, Kogiku, et al.
Publicado: (2023)

Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR
por: De, Nabanita, et al.
Publicado: (2008)

Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells
por: Sultana, Hameeda, et al.
Publicado: (2012)

Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion
por: Zeng, Jie, et al.
Publicado: (2021)

Phosphorylation of membrane-bound guanylate cyclase of sea urchin spermatozoa
Publicado: (1986)

Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii
por: Hunt, Alex, et al.
Publicado: (2019)

Distinct Roles of Soluble and Transmembrane Adenylyl Cyclases in the Regulation of Flagellar Motility in Ciona Sperm
por: Shiba, Kogiku, et al.
Publicado: (2014)

Extracellular Regulation of Sperm Transmembrane Adenylyl Cyclase by a Forward Motility Stimulating Protein
por: Dey, Souvik, et al.
Publicado: (2014)

An adenylyl cyclase with a phosphodiesterase domain in basal plants with a motile sperm system
por: Kasahara, Masahiro, et al.
Publicado: (2016)

Adenylyl Cyclase 1 Is Required for Ethanol-Induced Locomotor Sensitization and Associated Increases in NMDA Receptor Phosphorylation and Function in the Dorsal Medial Striatum
por: Bosse, Kelly E., et al.
Publicado: (2017)

CapG promoted nasopharyngeal carcinoma cell motility involving Rho motility pathway independent of ROCK
por: Fu, Ying, et al.
Publicado: (2022)

Resistin and adenylyl cyclase-associated protein 1 (CAP1) regulate the expression of genes related to insulin resistance in BNL CL.2 mouse liver cells
por: Avtanski, Dimiter, et al.
Publicado: (2019)

Prognostic impact of adenylyl cyclase-associated protein 2 (CAP2) in glioma: A clinicopathological study
por: Saker, Zahraa, et al.
Publicado: (2020)

Coactosin Phosphorylation Controls Entamoeba histolytica Cell Membrane Protrusions and Cell Motility
por: Hasan, Muhammad M., et al.
Publicado: (2020)

Distribution of adenylyl cyclase/cAMP phosphodiesterase gene, CAPE, in streptophytes reproducing via motile sperm
por: Yamamoto, Chiaki, et al.
Publicado: (2021)

Genomic Island-Encoded Diguanylate Cyclase from Vibrio alginolyticus Regulates Biofilm Formation and Motility in Pseudoalteromonas
por: Cai, Tongxuan, et al.
Publicado: (2023)

Thrombospondin-1 is a universal inhibitor of soluble guanylate cyclase activation
por: Miller, Thomas W, et al.
Publicado: (2009)

Antioxidant Assessment of Prenylated Stilbenoid-Rich Extracts from Elicited Hairy Root Cultures of Three Cultivars of Peanut (Arachis hypogaea)
por: Gajurel, Gaurav, et al.
Publicado: (2021)

CAPt’n of Actin Dynamics: Recent Advances in the Molecular, Developmental and Physiological Functions of Cyclase-Associated Protein (CAP)
por: Rust, Marco B., et al.
Publicado: (2020)

Effects of CapG overexpression on agonist-induced motility and second messenger generation
Publicado: (1995)

Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility
por: Fischer, Robert S., et al.
Publicado: (2003)

Adipocytes and Obesity-Related Conditions Jointly Promote Breast Cancer Cell Growth and Motility: Associations With CAP1 for Prognosis
por: Rosendahl, Ann H., et al.
Publicado: (2018)

Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects
por: Acin-Perez, Rebeca, et al.
Publicado: (2009)

Vicinal glutamates are better phosphomimetics: Phosphorylation is required for allosteric activation of guanylyl cyclase-A
por: Otto, Neil M., et al.
Publicado: (2022)

WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility
por: Howell, Michael, et al.
Publicado: (2015)

Enzymatically Active and Inactive Phosphodiesterases and Diguanylate Cyclases Are Involved in Regulation of Motility or Sessility in Escherichia coli CFT073
por: Spurbeck, Rachel R., et al.
Publicado: (2012)

The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility
por: Valentini, Martina, et al.
Publicado: (2016)

Functional Specialization in Vibrio cholerae Diguanylate Cyclases: Distinct Modes of Motility Suppression and c-di-GMP Production
por: Zamorano-Sánchez, David, et al.
Publicado: (2019)

Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells
por: Hofer, M D, et al.
Publicado: (2004)

E2F1-dependent methyl cap formation requires RNA pol II phosphorylation
por: Aregger, Michael, et al.
Publicado: (2012)

Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts
por: Kepser, Lara-Jane, et al.
Publicado: (2021)

A Functional Screen Provides Evidence for a Conserved, Regulatory, Juxtamembrane Phosphorylation Site in Guanylyl Cyclase A and B
por: Yoder, Andrea R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_sd9agc71im67u3brpitripq5dk