Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target()()

Approximately 50% of prostate cancers harbor the TMPRSS2:ERG fusion, resulting in elevated expression of the ERG transcription factor. Despite the identification of this subclass of prostate cancers, no personalized therapeutic strategies have achieved clinical implementation. Kinases are attractive...

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Detalles Bibliográficos
Autores principales: Lee, Rachel S, Zhang, Luxi, Berger, Adeline, Lawrence, Mitchell G, Song, Jiangning, Niranjan, Birunthi, Davies, Rebecca G, Lister, Natalie L, Sandhu, Shahneen K, Rubin, Mark A, Risbridger, Gail P, Taylor, Renea A, Rickman, David S, Horvath, Lisa G, Daly, Roger J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Short communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426874/
https://www.ncbi.nlm.nih.gov/pubmed/30901730
http://dx.doi.org/10.1016/j.neo.2019.02.005

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