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PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression

Lipid accumulation in macrophages interacts with microenvironment signals and accelerates diabetic atherosclerosis. However, the molecular mechanisms by which macrophage metabolism interacts with microenvironment signals during lipid accumulation are not clearly understood. Accordingly, an untargete...

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Detalles Bibliográficos
Autores principales: Ye, Guozhu, Gao, Han, Wang, Zhichao, Lin, Yi, Liao, Xu, Zhang, Han, Chi, Yulang, Zhu, Huimin, Dong, Sijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426939/
https://www.ncbi.nlm.nih.gov/pubmed/30674874
http://dx.doi.org/10.1038/s41419-018-1135-3