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PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression
Lipid accumulation in macrophages interacts with microenvironment signals and accelerates diabetic atherosclerosis. However, the molecular mechanisms by which macrophage metabolism interacts with microenvironment signals during lipid accumulation are not clearly understood. Accordingly, an untargete...
Autores principales: | Ye, Guozhu, Gao, Han, Wang, Zhichao, Lin, Yi, Liao, Xu, Zhang, Han, Chi, Yulang, Zhu, Huimin, Dong, Sijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426939/ https://www.ncbi.nlm.nih.gov/pubmed/30674874 http://dx.doi.org/10.1038/s41419-018-1135-3 |
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