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Vitamin C deficiency causes muscle atrophy and a deterioration in physical performance

L-Ascorbic acid (AsA) is a water-soluble antioxidant. We examined the effect of AsA deficiency on skeletal muscle using senescence marker protein-30 (SMP30)-knockout (KO) mice that are defective in AsA biosynthesis, which makes this mouse model similar to humans, to clarify the function of AsA in sk...

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Detalles Bibliográficos
Autores principales: Takisawa, Shoko, Funakoshi, Tomoko, Yatsu, Tomofumi, Nagata, Kisaburo, Aigaki, Toshiro, Machida, Shuichi, Ishigami, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426981/
https://www.ncbi.nlm.nih.gov/pubmed/30894591
http://dx.doi.org/10.1038/s41598-019-41229-7