Development of a (13)C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity

Dipeptidyl peptidase-4 inhibitors (DPP4i) are a class of orally available, small molecule inhibitors for the management of Type-II diabetes. A rapid, real-time, functional breath test for DPP4 enzyme activity could help to define DPP4i efficacy in patients that are refractory to treatment. We aimed...

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Detalles Bibliográficos
Autores principales: Yazbeck, Roger, Jaenisch, Simone, Squire, Michelle, Abbott, Catherine A., Parkinson-Lawrence, Emma, Brooks, Douglas A., Butler, Ross N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427020/
https://www.ncbi.nlm.nih.gov/pubmed/30894647
http://dx.doi.org/10.1038/s41598-019-41375-y

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