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Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance

Sensitivity is an important performance index for evaluating surface plasmon resonance (SPR) biosensors. Sensitivity enhancement has always been a hot topic. It is found that the different refractive indices of samples require different combinations of prism and metal film for better sensitivity. Fu...

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Detalles Bibliográficos
Autores principales: Xia, Guo, Zhou, Cuixia, Jin, Shiqun, Huang, Chan, Xing, Jinyu, Liu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427556/
https://www.ncbi.nlm.nih.gov/pubmed/30857251
http://dx.doi.org/10.3390/s19051198
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author Xia, Guo
Zhou, Cuixia
Jin, Shiqun
Huang, Chan
Xing, Jinyu
Liu, Zhijian
author_facet Xia, Guo
Zhou, Cuixia
Jin, Shiqun
Huang, Chan
Xing, Jinyu
Liu, Zhijian
author_sort Xia, Guo
collection PubMed
description Sensitivity is an important performance index for evaluating surface plasmon resonance (SPR) biosensors. Sensitivity enhancement has always been a hot topic. It is found that the different refractive indices of samples require different combinations of prism and metal film for better sensitivity. Furthermore, the sensitivity can be enhanced by coating two-dimensional (2D) materials with appropriate layers on the metal film. At this time, it is necessary to choose the best film configuration to enhance sensitivity. With the emergence of more and more 2D materials, selecting the best configuration manually is becoming more complicated. Compared with the traditional manual method of selecting materials and layers, this paper proposes an optimization method based on a genetic algorithm to quickly and effectively find the optimal film configuration that enhances sensitivity. By using this method, not only can the optimal number of layers of 2D materials be determined quickly, but also the optimal configuration can be conveniently found when many materials are available. The maximum sensitivity can reach 400°/RIU after optimization. The method provided application value for the relevant researchers seeking to enhance sensitivity.
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spelling pubmed-64275562019-04-15 Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance Xia, Guo Zhou, Cuixia Jin, Shiqun Huang, Chan Xing, Jinyu Liu, Zhijian Sensors (Basel) Article Sensitivity is an important performance index for evaluating surface plasmon resonance (SPR) biosensors. Sensitivity enhancement has always been a hot topic. It is found that the different refractive indices of samples require different combinations of prism and metal film for better sensitivity. Furthermore, the sensitivity can be enhanced by coating two-dimensional (2D) materials with appropriate layers on the metal film. At this time, it is necessary to choose the best film configuration to enhance sensitivity. With the emergence of more and more 2D materials, selecting the best configuration manually is becoming more complicated. Compared with the traditional manual method of selecting materials and layers, this paper proposes an optimization method based on a genetic algorithm to quickly and effectively find the optimal film configuration that enhances sensitivity. By using this method, not only can the optimal number of layers of 2D materials be determined quickly, but also the optimal configuration can be conveniently found when many materials are available. The maximum sensitivity can reach 400°/RIU after optimization. The method provided application value for the relevant researchers seeking to enhance sensitivity. MDPI 2019-03-08 /pmc/articles/PMC6427556/ /pubmed/30857251 http://dx.doi.org/10.3390/s19051198 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xia, Guo
Zhou, Cuixia
Jin, Shiqun
Huang, Chan
Xing, Jinyu
Liu, Zhijian
Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title_full Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title_fullStr Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title_full_unstemmed Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title_short Sensitivity Enhancement of Two-Dimensional Materials Based on Genetic Optimization in Surface Plasmon Resonance
title_sort sensitivity enhancement of two-dimensional materials based on genetic optimization in surface plasmon resonance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427556/
https://www.ncbi.nlm.nih.gov/pubmed/30857251
http://dx.doi.org/10.3390/s19051198
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