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Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response

Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years. Hirudin, a potent and specific thrombin inhibitor, has been report...

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Detalles Bibliográficos
Autores principales:	Deng, Fei, Zhang, Jingwei, Li, Yi, Wang, Wei, Hong, Daqing, Li, Guisen, Feng, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427573/ https://www.ncbi.nlm.nih.gov/pubmed/30880546 http://dx.doi.org/10.1080/0886022X.2019.1583113

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