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Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity
South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the recent past as a way of preventing the overproducti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427644/ https://www.ncbi.nlm.nih.gov/pubmed/30823479 http://dx.doi.org/10.3390/s19051035 |
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author | Etsassala, Ninon G.E.R. Waryo, Tesfaye Popoola, Olugbenga K. Adeloye, Adewale O. Iwuoha, Emmanuel I. Hussein, Ahmed A. |
author_facet | Etsassala, Ninon G.E.R. Waryo, Tesfaye Popoola, Olugbenga K. Adeloye, Adewale O. Iwuoha, Emmanuel I. Hussein, Ahmed A. |
author_sort | Etsassala, Ninon G.E.R. |
collection | PubMed |
description | South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the recent past as a way of preventing the overproduction of melanin in epidermal layers which often over time brings detrimental effects on human skin. In this present study, a fast screening method using a cyclic voltammetry technique was applied in the evaluation of methanolic extracts of twenty-five species of plants from the Lamiaceae family for anti-tyrosinase activity. Among these plants, those that showed a fast current inhibition rate at a minimum concentration when compared to a kojic acid standard were classified as having the greatest anti-tyrosinase activity. These include Salvia chamelaeagnea, S. dolomitica, Plectranthus ecklonii, P. namaensis, and P. zuluensis. The results presented herein focused in particular on providng firsthand information for further extensive research and exploration of natural product materials with anti-tyrosinase activity from South African flora for use in cosmetics, skin care and medicinal treatments. |
format | Online Article Text |
id | pubmed-6427644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64276442019-04-15 Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity Etsassala, Ninon G.E.R. Waryo, Tesfaye Popoola, Olugbenga K. Adeloye, Adewale O. Iwuoha, Emmanuel I. Hussein, Ahmed A. Sensors (Basel) Article South Africa is a country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. With wide applications in cosmetics, pharmaceuticals and food products, tyrosinase inhibitors have received very special attention in the recent past as a way of preventing the overproduction of melanin in epidermal layers which often over time brings detrimental effects on human skin. In this present study, a fast screening method using a cyclic voltammetry technique was applied in the evaluation of methanolic extracts of twenty-five species of plants from the Lamiaceae family for anti-tyrosinase activity. Among these plants, those that showed a fast current inhibition rate at a minimum concentration when compared to a kojic acid standard were classified as having the greatest anti-tyrosinase activity. These include Salvia chamelaeagnea, S. dolomitica, Plectranthus ecklonii, P. namaensis, and P. zuluensis. The results presented herein focused in particular on providng firsthand information for further extensive research and exploration of natural product materials with anti-tyrosinase activity from South African flora for use in cosmetics, skin care and medicinal treatments. MDPI 2019-02-28 /pmc/articles/PMC6427644/ /pubmed/30823479 http://dx.doi.org/10.3390/s19051035 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Etsassala, Ninon G.E.R. Waryo, Tesfaye Popoola, Olugbenga K. Adeloye, Adewale O. Iwuoha, Emmanuel I. Hussein, Ahmed A. Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title | Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title_full | Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title_fullStr | Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title_full_unstemmed | Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title_short | Electrochemical Screening and Evaluation of Lamiaceae Plant Species from South Africa with Potential Tyrosinase Activity |
title_sort | electrochemical screening and evaluation of lamiaceae plant species from south africa with potential tyrosinase activity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427644/ https://www.ncbi.nlm.nih.gov/pubmed/30823479 http://dx.doi.org/10.3390/s19051035 |
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