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PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics

Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performan...

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Autores principales: Costa, Adriana C., Pimenta, Sara, Ribeiro, João F., Silva, Manuel F., Wolffenbuttel, Reinoud F., Dong, Tao, Yang, Zhaochu, Correia, José H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427716/
https://www.ncbi.nlm.nih.gov/pubmed/30832271
http://dx.doi.org/10.3390/s19051057
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author Costa, Adriana C.
Pimenta, Sara
Ribeiro, João F.
Silva, Manuel F.
Wolffenbuttel, Reinoud F.
Dong, Tao
Yang, Zhaochu
Correia, José H.
author_facet Costa, Adriana C.
Pimenta, Sara
Ribeiro, João F.
Silva, Manuel F.
Wolffenbuttel, Reinoud F.
Dong, Tao
Yang, Zhaochu
Correia, José H.
author_sort Costa, Adriana C.
collection PubMed
description Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis.
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spelling pubmed-64277162019-04-15 PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics Costa, Adriana C. Pimenta, Sara Ribeiro, João F. Silva, Manuel F. Wolffenbuttel, Reinoud F. Dong, Tao Yang, Zhaochu Correia, José H. Sensors (Basel) Article Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis. MDPI 2019-03-01 /pmc/articles/PMC6427716/ /pubmed/30832271 http://dx.doi.org/10.3390/s19051057 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Costa, Adriana C.
Pimenta, Sara
Ribeiro, João F.
Silva, Manuel F.
Wolffenbuttel, Reinoud F.
Dong, Tao
Yang, Zhaochu
Correia, José H.
PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title_full PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title_fullStr PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title_full_unstemmed PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title_short PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
title_sort pdms microlenses for focusing light in narrow band imaging diagnostics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427716/
https://www.ncbi.nlm.nih.gov/pubmed/30832271
http://dx.doi.org/10.3390/s19051057
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