Cargando…
PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics
Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performan...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427716/ https://www.ncbi.nlm.nih.gov/pubmed/30832271 http://dx.doi.org/10.3390/s19051057 |
_version_ | 1783405274433847296 |
---|---|
author | Costa, Adriana C. Pimenta, Sara Ribeiro, João F. Silva, Manuel F. Wolffenbuttel, Reinoud F. Dong, Tao Yang, Zhaochu Correia, José H. |
author_facet | Costa, Adriana C. Pimenta, Sara Ribeiro, João F. Silva, Manuel F. Wolffenbuttel, Reinoud F. Dong, Tao Yang, Zhaochu Correia, José H. |
author_sort | Costa, Adriana C. |
collection | PubMed |
description | Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis. |
format | Online Article Text |
id | pubmed-6427716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64277162019-04-15 PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics Costa, Adriana C. Pimenta, Sara Ribeiro, João F. Silva, Manuel F. Wolffenbuttel, Reinoud F. Dong, Tao Yang, Zhaochu Correia, José H. Sensors (Basel) Article Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis. MDPI 2019-03-01 /pmc/articles/PMC6427716/ /pubmed/30832271 http://dx.doi.org/10.3390/s19051057 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Costa, Adriana C. Pimenta, Sara Ribeiro, João F. Silva, Manuel F. Wolffenbuttel, Reinoud F. Dong, Tao Yang, Zhaochu Correia, José H. PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title | PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title_full | PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title_fullStr | PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title_full_unstemmed | PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title_short | PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics |
title_sort | pdms microlenses for focusing light in narrow band imaging diagnostics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427716/ https://www.ncbi.nlm.nih.gov/pubmed/30832271 http://dx.doi.org/10.3390/s19051057 |
work_keys_str_mv | AT costaadrianac pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT pimentasara pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT ribeirojoaof pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT silvamanuelf pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT wolffenbuttelreinoudf pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT dongtao pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT yangzhaochu pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics AT correiajoseh pdmsmicrolensesforfocusinglightinnarrowbandimagingdiagnostics |