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Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis

Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference pa...

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Autores principales: Hubley, Lancia, Roberts, Jackson, Meyer, Juergen, Moggré, Alicia, Marsh, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427801/
https://www.ncbi.nlm.nih.gov/pubmed/30866546
http://dx.doi.org/10.3390/s19051167
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author Hubley, Lancia
Roberts, Jackson
Meyer, Juergen
Moggré, Alicia
Marsh, Steven
author_facet Hubley, Lancia
Roberts, Jackson
Meyer, Juergen
Moggré, Alicia
Marsh, Steven
author_sort Hubley, Lancia
collection PubMed
description Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference patterns resulting from variations in the refractive index as a function of the radiation-absorbed dose. Experiments conducted on prototype optical systems revealed the approach to be feasible but strongly dependent on environmental-influence quantities and setup configuration. A virtual dosimeter reflecting the prototype was created in a commercial optical modelling package. A number of virtual phantoms were developed to characterize the performance of the dosimeter under ideal conditions and with simulated disruptions in environmental-influence quantities, such as atmospheric and temperature perturbations as well as mechanical vibrations. Investigations into the error response revealed that slow drifts in atmospheric parameters and heat expansion caused the measured dose to vary between measurements, while atmospheric fluctuations and vibration contributed to system noise, significantly lowering the spatial resolution of the detector system. The impact of these effects was found to be largely mitigated with equalisation of the dosimeter’s reference and object path lengths, and by miniaturising the detector. Equalising path lengths resulted in a reduction of 97.5% and 96.9% in dosimetric error introduced by heat expansion and atmospheric drift, respectively, while miniaturisation of the dosimeter was found to reduce its sensitivity to vibrations and atmospheric turbulence by up to 41.7% and 54.5%, respectively. This work represents a novel approach to optical-detector refinement in which metrics from medical imaging were adapted into software and applied to a a virtual-detector system. This methodology was found to be well-suited for the optimization of a digital holographic interferometer.
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spelling pubmed-64278012019-04-15 Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis Hubley, Lancia Roberts, Jackson Meyer, Juergen Moggré, Alicia Marsh, Steven Sensors (Basel) Article Digital holographic interferometry (DHI) radiation dosimetry has been proposed as an experimental metrology technique for measuring absorbed radiation doses to water with high spatial resolution via noninvasive optical calorimetry. The process involves digitally recording consecutive interference patterns resulting from variations in the refractive index as a function of the radiation-absorbed dose. Experiments conducted on prototype optical systems revealed the approach to be feasible but strongly dependent on environmental-influence quantities and setup configuration. A virtual dosimeter reflecting the prototype was created in a commercial optical modelling package. A number of virtual phantoms were developed to characterize the performance of the dosimeter under ideal conditions and with simulated disruptions in environmental-influence quantities, such as atmospheric and temperature perturbations as well as mechanical vibrations. Investigations into the error response revealed that slow drifts in atmospheric parameters and heat expansion caused the measured dose to vary between measurements, while atmospheric fluctuations and vibration contributed to system noise, significantly lowering the spatial resolution of the detector system. The impact of these effects was found to be largely mitigated with equalisation of the dosimeter’s reference and object path lengths, and by miniaturising the detector. Equalising path lengths resulted in a reduction of 97.5% and 96.9% in dosimetric error introduced by heat expansion and atmospheric drift, respectively, while miniaturisation of the dosimeter was found to reduce its sensitivity to vibrations and atmospheric turbulence by up to 41.7% and 54.5%, respectively. This work represents a novel approach to optical-detector refinement in which metrics from medical imaging were adapted into software and applied to a a virtual-detector system. This methodology was found to be well-suited for the optimization of a digital holographic interferometer. MDPI 2019-03-07 /pmc/articles/PMC6427801/ /pubmed/30866546 http://dx.doi.org/10.3390/s19051167 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hubley, Lancia
Roberts, Jackson
Meyer, Juergen
Moggré, Alicia
Marsh, Steven
Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_full Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_fullStr Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_full_unstemmed Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_short Optical-Radiation-Calorimeter Refinement by Virtual-Sensitivity Analysis
title_sort optical-radiation-calorimeter refinement by virtual-sensitivity analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427801/
https://www.ncbi.nlm.nih.gov/pubmed/30866546
http://dx.doi.org/10.3390/s19051167
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