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Melissa: Bayesian clustering and imputation of single-cell methylomes

Measurements of single-cell methylation are revolutionizing our understanding of epigenetic control of gene expression, yet the intrinsic data sparsity limits the scope for quantitative analysis of such data. Here, we introduce Melissa (MEthyLation Inference for Single cell Analysis), a Bayesian hie...

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Detalles Bibliográficos
Autores principales:	Kapourani, Chantriolnt-Andreas, Sanguinetti, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427844/ https://www.ncbi.nlm.nih.gov/pubmed/30898142 http://dx.doi.org/10.1186/s13059-019-1665-8

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