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Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides
The ever-increasing bacterial genomic repositories reveal a great number of uncharacterized biosynthetic gene clusters, representing a tremendous resource for natural product discovery. Genome mining of the marine Streptomyces sp. NA03103 indicates the presence of an orphan nonribosomal peptide synt...
Autores principales: | Shi, Jing, Zeng, Ying Jie, Zhang, Bo, Shao, Fen Li, Chen, Yan Chi, Xu, Xiang, Sun, Yang, Xu, Qiang, Tan, Ren Xiang, Ge, Hui Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427947/ https://www.ncbi.nlm.nih.gov/pubmed/30996885 http://dx.doi.org/10.1039/c8sc05670f |
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