Structural and Dynamic Elucidation of a Non-acid PPARγ Partial Agonist: SR1988

Targeting peroxisome proliferator-activated receptor γ (PPARγ) by synthetic compounds has been shown to elicit insulin sensitising properties in type 2 diabetics. Treatment with a class of these compounds, the thiazolidinediones (TZDs), has shown adverse side effects such as weight gain, fluid reten...

Descripción completa

Detalles Bibliográficos
Autores principales: Frkic, Rebecca L., Chua, Benjamin S., Shin, Youseung, Pascal, Bruce D., Novick, Scott J., Kamenecka, Theodore M., Griffin, Patrick R., Bruning, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428214/
https://www.ncbi.nlm.nih.gov/pubmed/30906767
http://dx.doi.org/10.11131/2018/101350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428214/
https://www.ncbi.nlm.nih.gov/pubmed/30906767
http://dx.doi.org/10.11131/2018/101350

Ejemplares similares