Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

Genetic predictions of height differ among human populations and these differences have been interpreted as evidence of polygenic adaptation. These differences were first detected using SNPs genome-wide significantly associated with height, and shown to grow stronger when large numbers of sub-signif...

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Detalles Bibliográficos
Autores principales: Sohail, Mashaal, Maier, Robert M, Ganna, Andrea, Bloemendal, Alex, Martin, Alicia R, Turchin, Michael C, Chiang, Charleston WK, Hirschhorn, Joel, Daly, Mark J, Patterson, Nick, Neale, Benjamin, Mathieson, Iain, Reich, David, Sunyaev, Shamil R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428571/
https://www.ncbi.nlm.nih.gov/pubmed/30895926
http://dx.doi.org/10.7554/eLife.39702

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